WebAug 5, 2024 · Binds CD45 to mediate adhesion. Important for immune function and may be part of receptor complex for T-cell activation. CD44 60: Epican, HUTCH-I, LHR, PGP-1, ECMR-III, IN, INLU, MC56, MDU2, MIC4, MUTCH-1 ... Marker for cell-mediated lysis of target cells. Plays a role in the survival of NK cells against degranulation. 145: CD107b: … WebAs cell surface immunophenotype marker, CD45 is of great value in differentiation of lymphoproliferative diseases subtypes. By flow cytometry, based on CD45 expression, the malignant cell population is being identified and that fact is used in, not only diagnosis, but also in detection of minimal residual disease, especially in cases of CD45 ...
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CD45 is a pan-leukocyte protein with tyrosine phosphatase activity involved in the regulation of signal transduction in hematopoiesis. CD45 does not colocalize with lipid rafts on murine and human non-transformed hematopoietic cells, but CD45 positioning within lipid rafts is modified during their oncogenic … See more Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene. PTPRC is also known as CD45 antigen (CD stands for cluster of differentiation), … See more The protein product of this gene, best known as CD45, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular … See more PTPRC has been shown to interact with: • GANAB, • LYN, • Lck, and • SKAP1. CD45 has been recently shown to interact with the See more • Overview of all the structural information available in the PDB for UniProt: P08575 (Receptor-type tyrosine-protein phosphatase C) at the PDBe-KB. See more The CD45 protein family consists of multiple members that are all products of a single complex gene. This gene contains 34 exons, producing a massive protein with extracellular and … See more There are two identifiable alleles of CD45 in mice: CD45.1 (Ly5.1 historically) and CD45.2 (Ly5.2 historically). These two types of CD45 are … See more • Tchilian EZ, Beverley PC (2002). "CD45 in memory and disease". Archivum Immunologiae et Therapiae Experimentalis. 50 (2): 85–93. PMID 12024705 See more WebThe CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction. CD45R is commonly used as a pan B-cell marker; however, CD19 … ribbed sorority sweatshirt
Biotin anti-mouse/human CD45R/B220 Antibody anti-CD45R
WebThe CD45R isoform, also known as B220, is a highly expressed protein antigen expressed on the surface of most mouse B cells. It can be used to remove B cells from blood, PBMCs, or other sources of immune cells. The biotinylated anti-CD45R is used in the antibody cocktails in Akadeum’s Mouse T cell Isolation Kit, Mouse Naive T cell Isolation ... WebThe primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. ... Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers Molecular Family CD Molecules Antigen References 1. Barclay A , et al. 1997. … WebFor further information about CD45 and its isoforms refer to the CD45 mini-review . CD45R specifically has been shown to be essential in B cell receptor and T cell receptor signaling. It is primarily found on all … redhawks mascot