Phosphonoformate
WebPhosphonoformate and Phosphonoacetate are both pretty good mimics of the phosphate group: the 3-dimensional crystal structure is strikingly similar and the charge density distribution is similar. The carboxylic acid functional group of PFA and PAA is effective at hydrogen bonding in both the protonated and charged forms. WebAbstract. This article describes the antiviral properties of foscarnet (trisodium phosphonoformate) at the enzyme level as well as in cell cultures and in vivo. The …
Phosphonoformate
Did you know?
WebTrisodium phosphonoformate selectively inhibits cell-free DNA polymerase activity induced by herpesvirus. The new inhibitor has an antiviral effect on herpes simplex virus types 1 … WebDec 1, 1998 · Foscarnet (trisodium phosphonoformate)is an antiviral agent that has activity against herpesviruses,including cytomegalovirus (CMV),Epstein-Barr virus, herpes simplex virus (HSV) types 1 and 2, and varicella zoster virus (VZV). It also has activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV).
WebMar 25, 2006 · The first step in the preparation of appropriate synthons was condensation of bis ( N, N -diisopropylamino)phosphine and diphenylmethylsilylethyl chloroformate in the presence of sodium metal to yield formic acid, [bis ( N, N -diisopropylamino)phosphino]-β- (diphenylmethylsilylethyl) ester. WebSep 30, 1990 · Introduction Foscarnet (trisodium phosphonoformate) is an antiviral agent with in vitro activity against all known human herpesvirus and some retrovirus including human immunodeficiency virus (HIV) (Sandstrom …
WebFoscarnet impurity D. Synonym (s): Triethyl phosphonoformate, Ethyl diethoxyphospinylformate. Linear Formula: (C2H5O)2P (O)COOC2H5. CAS No.: 1474-78-8. WebTriethyl phosphonoformate for synthesis. CAS 1474-78-8, molar mass 210.17 g/mol. - Find MSDS or SDS, a COA, data sheets and more information.
Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium phosphonoformate).
WebTriethyl phosphonoformate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA CAS #: 1474-78-8 EC Number: 216-016-8 Molar Mass: 210.17 g/mol Hill Formula: C₇H₁₅O₅P 843410 View Pricing & Availability Recommended Products Overview Supporting Documentation Related Product … esxi 構成情報 バックアップ リストアWebPhosphonoformate Free Delivery on orders over USD 500 Bulk Inquiry? Quality Control & Documentation Purity: >97% COA MSDS Product Information Biological Activity Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs. Chemical Information esxi 構成情報 バックアップ サイズWebThese are: phosphite of acycloguanosine (P-ACG), Ara-A, cidofovir (CDV), ribavirin (Rib), phosphonoformate (PFA), glycyrrhizic acid (GLN) and alpha-interferon (alpha-IFN). All studied double combinations and triple combinations including P-ACV inhibited replication of both HSV strains more effectively than any drug alone. esxi 構成 バックアップWeb中文别名: 二乙氧基膦酰基甲酸乙酯;甲膦酸三乙酯;膦甲酸三乙酯: 英文别名: Ethyl Diethoxyphosphinylformate(cas:1474-78-8);Diethoxyphosphinylformic Acid Ethyl Ester/(Ethoxycarbonyl)phosphonic Acid Diethyl Ester/Triethyl Phosphonoformate esxi 無償版 制限 メモリWebJun 1, 2000 · Monoalkyl ether lipid analogues of foscarnet (phosphonoformate, PFA) exhibit substantially greater in vitro antiviral activity than unmodified PFA against human immunodeficiency virus type 1 (HIV-1). Our previous studies indicate that the length of the alkyl chain must be 14–22 carbons for optimal antiviral activity. esxi 構成情報 バックアップ 手順WebJul 1, 1995 · The effect of foscarnet (phosphonoformate) on human immunodeficiency virus isolation, T-cell subsets and lymphocyte function in AIDS patients. AIDS 1987;1:27-33. [561 Jacobson MA, O'Donnel JJ, Brodie HR, Wofsy C, Mills J. Randomized prospective trial of ganciclovir maintenance therapy for cytomegalovirus retinitis. J Med Virol 1988. [57] esxi 構成情報 リストアWebSodium phosphonoformate tribasic hexahydrate Synonym (s): Foscarnet, Phosphonoformic acid trisodium salt hexahydrate Linear Formula: Na2O3PCO2Na · 6H2O CAS No.: 34156-56-4 Molecular Weight: 300.04 Match Criteria: Product Name, Keyword All Photos ( … esxi 無償版 ダウンロード 方法