Web30. mar 2024 · The Sox9 gene is mapped on chromosome 17q24.3-q25.1 . belongs to the family of Sry related genes and encodes a protein consist of 80 amino acids . WebYou can see various sequences for this gene: cDNA (ENST00000245479.2) Protein (SOX9) Transcript and protein aligned (ENST00000245479.2+SOX9) Gene fusions. No fusions …
WikiGenes - SOX9 - SRY (sex determining region Y)-box 9
SOX9 is mostly localised in the nucleus and it is highly mobile. Studies in chondrocyte cell line has revealed nearly 50% of SOX9 is bound to DNA and it is directly regulated by external factors. Its half-time of residence on DNA is ~14 seconds. Zobraziť viac Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. Zobraziť viac SOX-9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It is expressed by proliferating but not hypertrophic chondrocytes … Zobraziť viac Mutations in Sox9 or any associated genes can cause reversal of sex and hermaphroditism (or intersexuality in humans). If Fgf9, which is activated by Sox9, is not present, a fetus with both X and Y chromosomes can develop female gonads; the … Zobraziť viac • SOX genes Zobraziť viac Mutations lead to the skeletal malformation syndrome campomelic dysplasia, frequently with autosomal sex-reversal and cleft palate. SOX9 sits in a gene desert on 17q24 in humans. Deletions, disruptions by translocation breakpoints … Zobraziť viac SOX9 has been shown to interact with Steroidogenic factor 1, MED12 and MAF. Zobraziť viac • Ninomiya S, Narahara K, Tsuji K, Yokoyama Y, Ito S, Seino Y (March 1995). "Acampomelic campomelic syndrome and sex reversal … Zobraziť viac WebThe 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. The PQA region (for proline, glutamine and alanine-rich) helps … gatheringdreams.com
SOX9 Gene - Somatic Mutations in Cancer - Wellcome Sanger …
WebThe Sox9 gene is mapped on chromosome 17q24.3-q25.1 belongs to the family of Sry related genes and encodes a protein consist of 80 amino acids of HMG domains of DNA … WebAbout 5 percent of cases are caused by chromosome abnormalities that occur near the SOX9 gene. These chromosome abnormalities disrupt regions of DNA called enhancers … Web10. máj 2004 · Sox-9 Organism names Organism Mus musculus (Mouse) Taxonomic identifier 10090 NCBI Taxonomic lineage Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus Accessions Primary accession … dawson and wearmouth